Life lies in exercise. As carriers of vital activities, biological macromolecules, atoms, molecules, single molecules and aggregates of molecules, whether in a liquid, gel, solid state, or in vitro, vivo or cells, all stay in motion state. The magnetic resonance and single molecule technologies are two of the representative technologies used to probe the dynamics of life at correlating ensemble and single molecule levels.

Organized by the Monomolecular Biology Academic Subgroup and the Biological Magnetic Resonance Academic Subgroup of the Biophysical Society of China, this session provides scientists in life dynamics studies with a platform for exchanges.

The study of dynamic properties of biological macromolecules at single-molecule and correlating ensemble levels offers new application scenarios for existing biophysical technologies. In addition, it promotes the development of new technologies and explores the essential laws of biological dynamics.

Chairmen

Guo Xuefeng

Professor, Peking University

Su Xuncheng

Professor, Nankai University

Invited speakers & reports

Liu Zheng

Professor, Wuhan University

Report: Lighting up the mechanical forces in living cells at the single-molecule level

Chen Wei

Professor, Zhejiang University

Report: Mechanical activation mechanism and blocking strategy of the novel coronavirus spike protein

Huang Shuo

Professor, Nanjing University

Report: Multiomics sequencing, structure elucidation and programmable single-molecule chemical reactors application of biomimetic nanochannels

Zhang Xinghua

Professor, Wuhan University

Report: Dam-methylation of DNA promotes both RecA assembly and homologous DNA pairing revealed by single-molecule experiments

Wu Haichen

Research fellow, Institute of Chemistry, Chinese Academy of Sciences

Report: Non-covalent interactions at the single-molecule level

Yu Zhongbo

Research fellow, Nankai University

Report: Single-molecule mechanism of dynamics of TRF1 organizing single-stranded telomeric DNA

Zeng Lei

Professor, The First Hospital of Jilin University

Report: Structural mechanism of BRD4-NUT fusion protein in hyperacetylation by p300

Lu Junxia

Research fellow, ShanghaiTech University

Report: The amyloid structures in cell necroptosis

Wang Shenlin

Professor, East China University of Science and Technology

Report: New methods for solid-state NMR spectroscopy of RNA

Jiang Yajun

Research fellow, Nanjing University

Report: Molecular chaperones in action

Shi Chaowei

Research fellow, University of Science and Technology of China

Report: Solid-state NMR studies on dynamics of membrane proteins

Yang Yin

Research fellow, Nankai University

Report: High-resolution DEER distance measurement on biological macromolecules