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Session 8: Neurobiophysics - Cell and Molecule/Circuit and System

Updated: 2022-08-18

  • Neurobiophysics — Cell and Molecule

Neurodegeneration is a progressive loss of function of neurons, which is present in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). There are common cellular pathways that are altered in these disorders, including loss of homeostasis in transcription regulation, misfolded protein clearance and mitochondrial function. Continuous research efforts should focus on understanding the cellular and molecular underpinnings behind these disorders and developing novel diagnostic and therapeutic targets for them.

This symposium session will invite six distinguished scientists in the field who have made recent significant discoveries in seeking to understand the cellular and molecular mechanisms of neurodegenerative diseases.



Liu Qiang

Professor, University of Science and Technology of China


Qi Shiqian

Professor, Sichuan University

Invited speakers & reports

Liu Xingguo

Research fellow, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

Report: Mitolysosome exocytosis: New approaches of mitochondrion quality control for Parkinson's disease

Jiao Jianwei

Research fellow, Institute of Zoology, Chinese Academy of Sciences

Report: Studies on neural stem cells and the mechanism of developmental brain diseases

Chai Renjie

Professor, Southeast University

Report: The potential application of Stem Cell transplantation in the Cochlear Implants

Xu Xiaojun

Research fellow, China Pharmaceutical University

Report: UPRmt activation for the treatment of Parkinson's disease

Kong Eryan

Professor, Xinxiang Medical University

Report: The roles of protein palmitoylation in neurodegenerative diseases

Liu Qiang

Professor, University of Science and Technology of China

Report: Epigenetic regulation of Alzheimer’s disease

  • Neurobiophysics — Circuit and System

Diverse neuron types are interconnected via local or long-range synapses to form distinct neural circuits, which are basic modules for different brain functions and behaviors. Dissecting the circuit connectivity and function is a fundamental demand for understanding how the brain works, especially in the era with the recent development of the state-of-the-art techniques in systematic visualization of neuronal circuits and functions such as serial Cryo-EM, micro-optical sectioning tomography (MOST), optogenetics, trans-synaptic viral tracing and in vivo large-scale electrophysiology or imaging of neuronal activity.

This symposium session will invite six renowned domestic system neuroscientists who have recently published very important discoveries in the field of neural circuits and systems in highly influential journals including Nature Neuroscience, Neuron, Nature Communications, and PNAS, to present the latest findings on the organization and function of brain circuits and even the whole-brain that underlies the sensation, learning and motivated behaviors as well as the maladaptive neural functions associated with neurological diseases.



Cao Peng

Research fellow, National Institute of Biological Sciences, Beijing


Xu Han

Professor, Zhejiang University

Invited speakers & reports

Li Xiaoming

Professor, Zhejiang University

Report: Studies on neural circuits of emotion and affective disorder

Wang Liping

Research fellow, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Report: Fear and sleep circuits

Zhang Zhi

Professor, University of Science and Technology of China

Report: Neural circuit mechanisms of targeted visual systems in pain regulation

Gao Zhihua

Professor, Zhejiang University

Report: Structures and functional analysis of hypothalamic neuroendocrine system

He Miao

Research fellow, Institutes of Brain Science, Fudan University

Report: Combinatorial genetic dissection of neural circuits

Zhan Cheng

Professor, University of Science and Technology of China

Report: Roles of hindbrain catecholaminergic neurons in control of energy metabolism