Mitochondria, as the powerhouses of the cells, regulate essential life processes, including redox homeostasis, calcium signaling and cell death. They play a central role in maintaining cellular homeostasis.

This session will closely align with national strategic needs and the frontier development of the subject, and delve into mitochondrial research through various novel technological approaches.

Based on research on mitochondrial functions, the session aims to better understand the essence of life activities, providing insights into major health-related issues such as diseases and aging.

The discussions will explore mitochondrial and nuclear anterograde and retrograde signaling, organelle interaction dynamics and immune responses – key regulatory events in cellular homeostasis – to uncover the mechanisms by which mitochondrial dysfunction leads to pathology, inflammation and aging.

Chairs

Zhu Yushan

Professor, Nankai University

Feng Du

Professor, Guangzhou Medical University

Invited speakers & reports

Guan Minxin

Professor, Zhejiang University

Report: Activation of mt-UPR by deafness-associated mitochondrial DNA mutation impacted mitochondrial and cellular homeostasis

Zhang Zhuohua

Professor, University of South China

Report: Mitochondria and aging

Yan Chuanzhu 

Professor, Qilu Hospital of Shandong University

Report: The role played by lactylation in regulating GDF15 in ME metabolic reprogramming

Feng Du

Professor, Guangzhou Medical University

Report: Nucleophagy: A new way of degrading cytoplasmic ectopic mtDNA

Shen Bin 

Professor, Nanjing Medical University

Report: Mitochondrial gene editing

Duan Liting

Professor, The Chinese University of Hong Kong

Report: Mechanical tension-induced mitochondrial tail self-cleavage and generation of matrix-free mitochondria-derived vesicles

Song Moshi

Researcher, Institute of Zoology, Chinese Academy of Sciences

Report: Research on mitochondrial regulation of cardiac homeostasis and aging

Gao Song

Sun Yat-sen University

Report: Mitochondrial fusion and T cell tumor immunity 

Sun Jianwei

Yunnan University

Report: Mitochondrial deoxyguanosine kinase and infertility