Through advancements in force measurement technology, glycan microarray technology, omics and structural biology, researchers are continually unraveling the complexities of glycan-protein recognition and interactions, particularly focusing on glycan clusters. These discoveries are paving the way for applications in diverse drug delivery systems.

One notable breakthrough is the development of a delivery system using GalNAc derivative structures to transport small interfering RNAs (siRNAs) to the liver, marking a significant milestone in the clinical application of siRNAs. These innovations will be highlighted in the upcoming session, showcasing the latest advancements in this field.

Chair

Wang Peng

Chair professor, Southern University of Science and Technology (SUSTech)

Invited speakers & reports

Zong Chengli

Professor, Hainan University

Report: Total chemical synthesis of heparin molecules and their utilization as drug carriers

Ye Mingliang

Researcher, Dalian Institute of Chemical Physics, Chinese Academy of Sciences

Report: Energy state difference-based new methods for drug target identification and their potential applications in research on the mechanism of polysaccharide drugs

Fang Junqiang

Professor, Shandong University

Report: Chemo-enzymatic methods for the synthesis and applications of functional oligosaccharides

Liu Xuewei

Professor, Nanyang Technological University

Report: TBA

Tao Shengce

Professor, Shanghai Jiao Tong University

Report: Novel proximal labeling technique (SPIDER) for discovering biomolecular interaction proteins

Wu Zhongfu

Professor, Northwest University

Report: ANPMP labeling-based construction and applications of natural oligosaccharide chips 

Wang Peng

Chair professor, SUSTech

Report: TBA

Yu Xing  

Hunan Normal University

Report: Unveiling the multifunctionality of heparanase: Enzymatic and non-enzymatic roles in tumor biology and bioengineering