The Fourth Conference on Bioinformatics and Translational Medicine (CBTM2026) was grandly inaugurated at the Huairou Urban Lounge in Beijing. Jointly organized by the Biomedical Information Branch of the Biophysical Society of China, the Multidisciplinary Center for Biological Intelligence at the Chinese Academy of Sciences, and the Beijing Medical Association, the event was co-hosted by several prominent institutions including Peking University People's Hospital and the Chinese Society of Automation's Intelligent Health and Bioinformatics Committee.

The conference, chaired by experts such as Dr. Bo Xiaocheng from the Academy of Military Medical Sciences, focused on the theme "Translational Medicine in the Era of Digital Intelligence." On June 13, the main forum gathered experts from academia, research institutions, healthcare, and industry to explore the innovative applications of AI and big data in biomedical research and clinical translation. Dr. Wang Jianliu, one of the conference chairs, emphasized in his opening speech the pivotal role of digital intelligence in bridging research, clinical practice, and industry.

The main forum featured insightful presentations by eminent academicians. Academician Chen Runsheng shared his perspectives on AI in life sciences, while Academician Wang Jianwei discussed AI's role in infectious disease surveillance. Dr. Wang Jianliu presented advancements in the precision diagnosis and treatment of endometrial cancer.

On June 14, eight specialized forums delved into topics like infectious disease prevention, translational medicine, and AI-driven clinical applications. These sessions fostered vibrant discussions, creating a platform for interdisciplinary dialogue across research, clinical, and industrial domains.

A notable highlight was the debut of the "Lixianghui" thematic salon, designed to encourage cross-disciplinary brainstorming in a relaxed setting. This initiative aimed to break academic silos and promote the seamless integration of research and industry.

CBTM continues to be a leading platform for advancing the intersection of bioinformatics and translational medicine, driving innovation and collaboration across sectors.